How to Approach a Responsive Design | Upstatement.
A must read:
So we lined up the usual suspects from Adobe. Who would be our partner in crime — Photoshop? Illustrator? InDesign?
Hands down, the answer was InDesign. At its core, BostonGlobe.com is a publication website, and InDesign is the best tool for laying out publications and content. Yes, there are huge differences between designing print publications and designing for the web, but consider this: Most web pages are simply a combination of photos and text. And where Photoshop excels at manipulating images (but sucks at type) and Illustrator is exceptional at typography (but sucks with images), InDesign is built for both……
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